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What are the potential side effects of GLP-1 agonists and dual GIP/GLP-1 receptor agonists?
What are the potential side effects of GLP-1 agonists and dual GIP/GLP-1 receptor agonists?
Updated over 2 months ago

Common side effects of semaglutide/tirzepatide include:

  • Nausea

  • Stomach pain

  • Diarrhoea

  • Vomiting

  • Constipation

  • Headache

  • Tiredness

  • Belching

  • Dizziness

  • Bloating

  • Gas

  • Upset stomach

  • Heartburn

  • Hair loss

These effects tend to resolve over time as your body adjusts to the medication and dose. If you are struggling with the side effects, our clinicians are on hand to support and advise you.


Rare or uncommon side effects of semaglutide/tirzepatide include:

  • Pancreatitis (inflammation of the pancreas)

  • Gallstones

  • Hypoglycemia (low blood sugar) in patients with type 2 diabetes

  • Anaphylactic/ allergic reaction

  • Diabetic retinopathy (an eye condition) complications in patients with type 2 diabetes (semaglutide)

  • Palpitations or feelings of a racing heartbeat while at rest

If you experience any of the serious side effects listed above, seek medical attention immediately and stop taking the medication if prescribed.

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